Registration Dossier

Administrative data

Endpoint:
short-term toxicity to birds: acute oral toxicity test (LD50-only)
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
Not specified in publication
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
publication
Title:
The acute oral toxicity, repellency and hazard potential of 998 chemicals to one or more species of wild and domestic birds
Author:
Schafer EW, Bowles WA, Hulbut J
Year:
1983
Bibliographic source:
Arch. Environ. Contam. Toxicol.

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Wild-trapped birds were dosed by gavage with solutions or suspensions of the test material
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Specific details on test material used for the study:
Test material info not available
Dose method:
gavage
Analytical monitoring:
no
Vehicle:
yes
Remarks:
propylene glycol

Test organisms

Test organisms (species):
other: wild-trapped birds
Details on test organisms:
- Preconditioned to captivity: 2 to 6h

Study design

Limit test:
no

Results and discussion

Effect levels
Dose descriptor:
LC50
Effect level:
316 mg/kg bw
Conc. / dose based on:
test mat.
Basis for effect:
mortality

Applicant's summary and conclusion

Validity criteria fulfilled:
no
Conclusions:
The effect of the test item on birds was assessed. The reported LD50 is 316 mg/kg body weight.
Executive summary:

The acute oral toxicity of 1,2 -dihydroxyanthraquinone was assessed. Wild-trapped birds were pre- conditioned to captivity for 2 to 6 weeks and were dosed by gavage with solutions or suspension of the test chemical in propylene glycol. The reported LD50 is 316 mg/kg body weight.