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EC number: 297-025-4
CAS number: 93281-13-1
Time after treatment (hrs)
X = sign observed
- = observation performed, sign not
(G) = max. grade
The purpose of the dermal toxicity study
was to assess the toxicological profile of test item when administered
to rats by a single semi-occlusive dermal application, with an
observation period of 15 days. The test was perfromed accodring to the
OECD guideline 402. The test article was applied to the skin of rats of
both sexes for 24 hours at a single dose of 2000 mg/kg bw. The substance
was removed after 24 hours exposure and the skin was washed. All the
animals were subjected to necropsy at the end of the observation period.
No dead occurred during the experiment and
no macroscopic findings were noted. All animals, showed a black-coloured
back, from the 2nd day until the end of the observation period, but no
LD50 (males and female) > 2000 mg/kg bw
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