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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin sensitisation

Currently viewing:

Administrative data

Endpoint:
skin sensitisation, other
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Read-across study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
See attached for read-across supporting information.

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2011
Report date:
2011

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
Read across to 2,6-dichloro-4-nitroaniline JMPR evaluation
GLP compliance:
not specified
Remarks:
Data from collection/ handbook, no informaiton on completion date or compliace is available.
Type of study:
other: Read across to 2,6-dichloro-4-nitroaniline JMPR evaluation

Test material

Constituent 1
Chemical structure
Reference substance name:
2,6-dichloro-4-nitroaniline
EC Number:
202-746-4
EC Name:
2,6-dichloro-4-nitroaniline
Cas Number:
99-30-9
Molecular formula:
C6H4Cl2N2O2
IUPAC Name:
2,6-dichloro-4-nitroaniline
Test material form:
solid
Details on test material:
Molecule for read-across studies
Specific details on test material used for the study:
Test material specifics not available, read-across from collection of data.

In vivo test system

Test animals

Species:
other: Not specified
Strain:
not specified
Sex:
not specified

Results and discussion

In vivo (non-LLNA)

Results
Key result
Reading:
other: Not Specified, final result only available
Group:
other: Not Specified, final result only available
Clinical observations:
None specified, final result only available
Remarks on result:
positive indication of skin sensitisation
Remarks:
Not sensitising (JMPR evaluation) Method of evaluation (in vivo/ vitro/ chemico) not specified in summary report

Any other information on results incl. tables

Not sensitising (JMPR evaluation) Method of evaluation (in vivo/ vitro/ chemico) not specified in summary report.

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
The compound 2,6-dichloro-4-nitroaniline was not found to be a skin sensitizer, and therefore has no skin sensitization classification under CLP (1272/2008)
Executive summary:

The compound 2,6-dichloro-4-nitroaniline was not found to be a skin sensitizer, and therefore has no skin sensitization classification under CLP (1272/2008)