Registration Dossier
Registration Dossier
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EC number: 201-317-9 | CAS number: 81-04-9
Endpoint summary
Administrative data
Description of key information
There are no data on naphathalene-1,5-disulfonic acid available.
There are data on the disudium salt (disodium-naphthalene-1,5-disulphonate; CAS-No. 1655-29-4) available. The available information does not point to a skin sensitization potential in vivo. No protein binding alert was obtained via in silico assessment with the OECD Toolbox. The disodium salt was tested in chemico for the first key event of skin sensitization (peptide reactivity) and in vitro for the second key event (keratinocyte activation). Both tests revealed negative results. A third test (activation of dendritic cells) is ongoing.
Key value for chemical safety assessment
Justification for classification or non-classification
The above listed tests for the disodium salt are adequate for non-classification regarding skin sensitization and risk assessment according to point 8.3 of Annex VII of Regulation (EC) 1907/2006.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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