Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2017
Report Date:
2017

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
4.106
Temp.:
35 °C
pH:
7

Any other information on results incl. tables

Product

Experimental Log POW  
HPLC (MSC)

Calculated Log POW 
 (ECOSAR) with CAS number

Miramer M1086

 =Di(ethylene glycol) 2-ethylhexyl acrylate

4.106 (88.95%)

3.543

Applicant's summary and conclusion

Conclusions:
A solution of the test substance is injected onto a reversed-phase HPLC column with UV detection. The Log POW value is calculated from the retention time of the test substance. For the major component, Log POW value is 4.705 (64.02% of total base peak area). For the minor components, Log POW values are between 0.298 and 4.705.