Registration Dossier
Registration Dossier
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EC number: 219-135-3 | CAS number: 2370-63-0
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012-07-25 to 2012-07-31
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Version / remarks:
- May 2008
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Version / remarks:
- adopted 13 April 2004
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 1.8
- Temp.:
- 23.3 °C
- Remarks on result:
- other: pH not determined
- Conclusions:
- The log Pow of ETMA is reported to be 1.8 at 23.3°C.
- Executive summary:
The n-Octanol/Water partition coefficient (log Pow) of ETMA was determined according to OECD Guideline 117, adopted 13 April 2004, and EU Method A.8, 30 May 2008; HPLC method. The log Pow was 1.8 at 23.3°C.
Reference
Reference item |
Retention time |
Mean Retention time |
logPOW
|
2-Butanone |
1.899 |
1.900 |
0.3 |
1.901 |
|||
Benzyl alcohol |
2.380 |
2.381 |
1.1 |
2.381 |
|||
Benzonitrile |
3.314 |
3.315 |
1.6 |
3.316 |
|||
Methyl benzoate |
6.204 |
6.206 |
2.1 |
6.208 |
|||
Atrazine |
6.606 |
6.608 |
2.6 |
6.610 |
|||
Chlorobenzene |
12.717 |
12.726 |
2.8 |
12.735 |
|||
Phenyl benzoate |
22.981 |
23.013 |
3.6 |
23.044 |
Description of key information
The n-Octanol/Water partition coefficient (log Pow) of ETMA is 1.8 at 23.3°C (OECD Guideline 117/EU Method A.8; HPLC method).
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 1.8
- at the temperature of:
- 23.3 °C
Additional information
The n-Octanol/Water partition coefficient (log Pow) of ETMA was determined according toOECD Guideline 117, adopted 13 April 2004, and EU Method A.8, 30 May 2008; HPLC method. The log Pow was 1.8 at 23.3°C.
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