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Environmental fate & pathways

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Bioaccumulation:aquatic/sediments:

Using BCFBAF Program (v3.00) model of EPI suite 2017 the estimated bio concentration factor (BCF) for 4-[(3-aminobenzoyl)amino]-5-hydroxynaphthalene-1,7-disulphonic acid (CAS No. 70239-77-9) is 3.162 L/kg wet-wt at 25 deg. c which does not exceed the bioconcentration threshold of 2000. Therefore it is concluded that test chemical 4-[(3-aminobenzoyl)amino]-5-hydroxynaphthalene-1,7-disulphonic acid is non bioaccumulative in food chain.

Additional information

Bioaccumulation:aquatic/sediments:

Different predicted data studies have been conducted for target chemical 4-[(3-aminobenzoyl)amino]-5-hydroxynaphthalene-1,7-disulfonic acid (CAS no.70239-77-9) and their results are summarized below.

 

The first weight of evidence study was done by using BCFBAF Program (v3.00) model of Estimation Program Interface (EPI suite 2017) the estimated bio concentration factor (BCF) for 4-[(3-aminobenzoyl)amino]-5-hydroxynaphthalene-1,7-disulphonic acid (CAS No. 70239-77-9) is 3.162 L/kg wet-wt at 25 deg. c which does not exceed the bioconcentration threshold of 2000.

 

Another weight of evidence study was done by using Bio-concentration Factor (v12.1.0.50374) module of Advanced Chemistry Development/I-lab predictive module in this study Bio-concentration Factor at range pH 1-14  of the chemical 4-[(3-aminobenzoyl)amino]-5-hydroxynaphthalene-1,7-disulphonic acid (CAS no.70239 -77 -9) estimated to be 1.00 dimensionless.

 

Next weight of evidence study was done by using SciFinder Database of American Chemical Society (ACS, 2017) in this study the Bioconcentration factor (BCF) for test chemical 4-[(3-aminobenzoyl)amino]-5-hydroxynaphthalene-1,7-disulphonic acid (CAS No: 70239-77-9) was predicted in aquatic organisms at pH 1-10 and temperature 25 °C .The Bioconcentration factor (BCF) of test substance 4-[(3-aminobenzoyl)amino]-5-hydroxynaphthalene-1,7-disulphonic acid at pH 1-10 and temperature 25 °C was estimated to be 1.00 dimensionless.  

 

Last weight of study was done by using  Chemspider- ACD/PhysChem Suite of Royal Society of Chemistry (RCS, 2017) in this study the Bioconcentration factor (BCF) for test chemical 4-[(3-aminobenzoyl)amino]-5-hydroxynaphthalene-1,7-disulphonic acid (CAS No: 70239-77-9) was predicted in aquatic organisms at pH 5.5 and pH 7.4.The Bioconcentration factor (BCF) of test substance  at pH 5.5 and pH 7.4 was estimated to be 1.00 dimensionless. 

 

On the basis of all the studies mentioned above it is concluded that BCF value of the test chemical 4-[(3-aminobenzoyl)amino]-5-hydroxynaphthalene-1,7-disulphonic acid  falls in range of 1-3.162 dimensionless and this test chemical is considered as non bioaccumulative in aquatic organisms as BCF value does not exceeds 2000 criteria.