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Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

Based on nominal WAF loading rates and immobility data, the EL50 was determined to be 71 mg/L. The no-immobility loading rate was 13 mg/L and the no-observed effect loading rate was 13 mg/L. Based on mean measured WAF loading rates and immobility data, the EL50 was determined to be 30 mg/L. The no-immobility loading rate was 8.9 mg/L and the no-observed effect loading rate was 8.9 mg/L (OECD 202, OPPTS 850.1010 and ASTM E729 -96)..

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
30 mg/L

Additional information

GUIDELINE

The study protocol was based on procedures outlined in the OECD Guidelines for Testing of Chemicals, Guideline 202: Daphnia sp., Acute Immobilization Test; U.S. Environmental Protection Agency Series 850 - Ecological Effects Test Guidelines (draft), OPPTS Number 850.1010: Aquatic Invertebrate Acute Toxicity Test, Freshwater Daphnids; and ASTM Standard E729-96: Standard Guide for Conducting Acute Toxicity Tests on Test Materials with Fishes, Macroinvertebrates and Amphibians.

 

METHODS

The cladoceran, Daphnia magna, was exposed for 48 hours under static conditions to five nominal WAF loading rates of test item ranging from 13 to 200 mg/L.

 

RESULTS

Based on nominal WAF loading rates and immobility data, the EL50 was determined to be 71 mg/L. The no-immobility loading rate was 13 mg/L and the no-observed effect loading rate was 13 mg/L. Based on mean measured WAF loading rates and immobility data, the EL50 was determined to be 30 mg/L. The no-immobility loading rate was 8.9 mg/L and the no-observed effect loading rate was 8.9 mg/L.