2-anilinoethanol

Short-term toxicity to fish

Link to relevant study record(s)

Reference

Endpoint:

short-term toxicity to fish

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Study performed according to national standards. Limitations in design and reporting but results considered reliable and adequate for assessment.

Qualifier:

according to guideline

Guideline:

other: DIN 38 412

GLP compliance:

no

Analytical monitoring:

no

Vehicle:

no

Test organisms (species):

Leuciscus idus

Details on test organisms:

PRE-TEST CONDITIONS:
- Common name: Golden orfe
- Source: Fa. P. Eggers, Hohenwestedt bei Neumuenster, BRD (07-10-1980)
- Weight: 2.3 g
- Length: 6.4 cm
- Caging: in dechlorinated tap water; continuous aeration with oil-free air
- Feed: Fukosalm-anschlussfutter 1 (Fuko - Kraftfutterfabrik, Ulm, BRD) ad libitum
- Medical treatment during last 4 weeks: none

ACCLIMATION
- Acclimation period: 3 days

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

96

Remarks on exposure duration:

h

Hardness:

1.3-2.6 mmol/L

Test temperature:

20±1°C

pH:

t=0h: 7.2-7.6
t=96h: 6.9-7.4

Dissolved oxygen:

t=0h: 8.1-9.1 mg O2/L
t=96h: 6.9-9.1 mg O2/L

Nominal and measured concentrations:

- Nominal: 68.4, 100, 147, 215, 316, 464 anf 681 mg/L.

Details on test conditions:

TEST SYSTEM
- Test vessel: 10L glass tanks (30 cm x 22 cm x 24 cm)
- Aeration: yes, continuous with oil-free air
- No. of organisms per vessel: 10

Reference substance (positive control):

yes

Remarks:

Chloracetamide

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

> 464 - < 681 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Details on results:

- Deaths were observed only at the highest tested concentration of 681 mg/L (100% mortality within 1 hour after exposure).
- Symptoms such as narcose-like condition, site location and stagger were observed at the 464 mg/L test concentration.

Results with reference substance (positive control):

- 48-h LC50: ca. 26 mg/L

Reported statistics and error estimates:

Finney, D.J. Probit analysis, Cambridge University Press (1971).

Description of key information

With high propability acutely not harmful to fish.

Additional information

Acute toxicity to fish was tested in a study according to DIN 38412 dated March 3rd 1981 (BASF AG, study report number 80/476; non-GLP). The species under study was Gorden Orfe and the static test resulted in an LC50 >100 mg/L after a test duration of 96h.