2-anilinoethanol

Biodegradation in water: screening tests

Link to relevant study record(s)

Reference

Endpoint:

biodegradation in water: ready biodegradability

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study performed according to OECD guidance and in compliance with GLP criteria.

Qualifier:

according to guideline

Guideline:

OECD Guideline 301 A (Ready Biodegradability: DOC Die Away Test)

Qualifier:

according to guideline

Guideline:

EU Method C.4-A (Determination of the "Ready" Biodegradability - Dissolved Organic Carbon (DOC) Die-Away Test)

Qualifier:

according to guideline

Guideline:

ISO 7827 (Evaluation in an Aqueous Medium of the "Ultimate" Aerobic Biodegradability of Organic Compounds - Method by Analysis of Dissolved Organic Carbon (DOC))

GLP compliance:

yes (incl. QA statement)

Remarks:

BASF Aktiengesellschaft, Experimental Toxicology and Ecology, 67056 Ludwigshafen/Rhein, Germany

Oxygen conditions:

aerobic

Inoculum or test system:

activated sludge, domestic (adaptation not specified)

Details on inoculum:

Activated sludge from Iaboratory wastewater plant treating municipal sewage. Concentration of activated sludge in the test assay: 30 mg/L (dry substance).

Duration of test (contact time):

35 d

Initial conc.:

29 mg/L

Based on:

test mat.

Initial conc.:

20 mg/L

Based on:

DOC

Details on study design:

- Test temperature: 22 ± 2 °C

Reference substance:

aniline

Test performance:

- Degradation degree of the reference substance after 14 days (% DOC): 90-100.
- Degradation degree in the inhibition control after 14 days (% DOC): 70-80.
- Physico-chemnical (abiotic) elimination of the test substance (% DOC): <10 at the end of the test.
- Elimination of the test substance by adsorption (% DOC): <10 after 5 days

Parameter:

% degradation (DOC removal)

Value:

> 70 - < 80

Sampling time:

28 d

Remarks on result:

other: 10-day window not met.

Details on results:

- 10-day window: 10% degradation was reached between 3 and 5 days, 70% degradation was reached between 27 and 28 days.

DOC-degree [%]:

Day	RS	IH	PC	AC	TS1	TS2	TS mv
0	0	0	0	0	0	0	0
1	4	2	0	0	-4	-2	-3
3	84	24	-3	-3	3	1	2
5	91	62	3	2	19	12	16
7	91	72	1		27	13	20
10	91	77	1		37	26	32
14	94	80	-5		45	31	38
17	93	81	-8		50	31	41
21	94	86	-3		54	38	46
24	96	88	0		60	48	54
27	97	90	4		69	60	65
28	99	91	-7		75	67	71
31	103	98	-2		102	102	102
34	98	99	5		94	97	96
35	97	99	0		95	98	97

Legend: BC = RS =reference substance; IH =inhibition control; AC =adsorption control; PC = abiotic control; TS =test substance; mv = mean value

Validity criteria fulfilled:

yes

Interpretation of results:

other: Biodegradable, but not readily biodegradable

Conclusions:

The substance is biodegradable but failing the 10-day window.

Description of key information

Readily biodegradable, but failing 10-day window.

Key value for chemical safety assessment

Biodegradation in water:

readily biodegradable but failing 10-day window

Additional information

2-Aminoethanol was investigated in a GLP-Study follwoing OECD 301A in 2003 (BASF SE, study number 02/0625/21/1). The study was run with activated sludge of domestic origin. After 28 days, 70% degradation was reached expressed as DOC removal. However, the 10-day window was not met.