Yttrium(3+) acetate

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

11 September 2017 to 02 November 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Version / remarks:

1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Version / remarks:

2008

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Key result

Water solubility:

100 g/L

Conc. based on:

test mat.

Remarks:

(tetrahydrate)

Temp.:

20 °C

pH:

5.6

Details on results:

Preliminary Test
- The estimate of the water solubility at 20.0 ± 0.5 °C was 27.9 gY/L, 83.6 g/L as equivalent anhydrous yttrium acetate and 106 g/L as equivalent yttrium acetate tetrahydrate. The pH of the solution was 5.9.
 
Definitive Test
- The counts per second relating to the standard and sample solutions are shown in Tables 1 and 2.
- Mean results at 20.0 ± 0.5°C:
As yttrium: 26.3 gY/L
As equivalent anhydrous yttrium acetate 78.7 g/L
As equivalent yttrium acetate tetrahydrate 100 g/L
 
Discussion
- On completion of the definitive test equilibration period, the samples had excess, undissolved test material present. After filtration, the samples were observed to be visually clear, colourless solutions with no definitive Tyndall beam effect.
- The yttrium (88.9 amu) concentrations were corrected to “as equivalent anhydrous yttrium acetate” (266.0 amu) and “as yttrium acetate tetrahydrate” (338.1 amu) using the masses shown in brackets.

Table 1: Counts per Second

Solution	Counts per Second
	Yttrium	Internal Standard
Standard 1.00 mg/L	8841699.9	141497.6
Standard 2.50 mg/L	22318183.6	141826.7
Standard 5.01 mg/L	44122217.1	141110.7
Standard 10.01 mg/L	87575144.3	139761.7
Standard 10.01 mg/L	87850364.2	139825.2
Standard 15.02 mg/L	130385040.3	137505.2
Standard 20.02 mg/L	171071016.3	134927.9
Matrix blank	71262.4	135839.6
Sample 1A	96496754.1	135732.3
Sample 1B	96801305.2	136288.5
Sample 2A	78273639.9	135331.5
Sample 2B	90111975.3	136395.5
Sample 3A	94136250.8	136315.0
Sample 3B	86989153.1	137865.0

 

Table 2: Concentration of the test material in the sample solutions

Sample Number	Concentration (g/L)			Solution pH
	As Yttrium	As Equivalent Anhydrous Yttrium Acetate	As Equivalent Yttrium Acetate Tetrahydrate
1	28.2	84.3	107	5.6
2	24.6	73.5	93.4	5.6
3	26.2	78.4	99.7	5.6

 

Conclusions:

Under the conditions of this study, the water solubility of the test material has been determined at 20.0 ± 0.5 °C to be 100 g/L based on the test material being yttrium acetate tetrahydrate.

Executive summary:

The water solubility of the test material was determined in accordance with the standardised guidelines OECD 105 and EU Method A.6, under GLP conditions.

The shake flask method was performed and the samples were analysed using inductively coupled plasma mass spectrometry (ICP-MS).

On completion of the definitive test equilibration period, the samples had excess, undissolved test material present. After filtration, the samples were observed to be visually clear, colourless solutions with no definitive Tyndall beam effect.

The mean results at 20.0 ± 0.5 °C were: as yttrium: 26.3 gY/L, as equivalent anhydrous yttrium acetate 78.7 g/L and as equivalent yttrium acetate tetrahydrate 100 g/L

Under the conditions of this study, the water solubility of the test material has been determined at 20.0 ± 0.5 °C to be 100 g/L based on the test material being yttrium acetate tetrahydrate.

Description of key information

Under the conditions of this study, the water solubility of the test material has been determined at 20.0 ± 0.5 °C to be 100 g/L based on the test material being yttrium acetate tetrahydrate.

Key value for chemical safety assessment

Water solubility:

100 g/L

at the temperature of:

20 °C

Additional information

The water solubility of the test material was determined in accordance with the standardised guidelines OECD 105 and EU Method A.6, under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).

The shake flask method was performed and the samples were analysed using inductively coupled plasma mass spectrometry (ICP-MS).

On completion of the definitive test equilibration period, the samples had excess, undissolved test material present. After filtration, the samples were observed to be visually clear, colourless solutions with no definitive Tyndall beam effect.

The mean results at 20.0 ± 0.5 °C were: as yttrium: 26.3 gY/L, as equivalent anhydrous yttrium acetate 78.7 g/L and as equivalent yttrium acetate tetrahydrate 100 g/L

Under the conditions of this study, the water solubility of the test material has been determined at 20.0 ± 0.5 °C to be 100 g/L based on the test material being yttrium acetate tetrahydrate.