Registration Dossier

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Currently viewing:

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1992
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1992
Report Date:
1992

Materials and methods

Test guideline
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
no
Details on test solutions:
The test substance was dissolved in test medium to form a stock solution which was diluted to concentrations of 0.032, 0.1, 0.316, 1 mg/L.

Test organisms

Test organisms (species):
Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
72 h

Test conditions

pH:
8.6 - 10.5
Reference substance (positive control):
not specified

Results and discussion

Effect concentrationsopen allclose all
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
0.14 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
biomass
Remarks on result:
other: CL: 0.02-0.57
Duration:
72 h
Dose descriptor:
EC10
Effect conc.:
0.03 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
biomass
Remarks on result:
other: CL: 0-0.09
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
0.21 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
EC10
Effect conc.:
0.02 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
An algal growth inhibition test was performed using four test concentrations between 0.032 mg/L and 1 mg/L. Based on biomass and growth rate, EC50 values of 0.14 mg/L and 0.21 mg/L were determined, respectively.
Executive summary:

To investigate potential harmful effects of the test item on aquatic algae or cyanobacteria, an algal growth inhibition test was performed. The test was performed with four test concentrations between 0.032 mg/L and 1 mg/L. With regard to biomass and growth rate, EC50 (72h) values of 0.14 mg/L and 0.21 mg/L were determined, respectively. The ErC10 (72 h) was determined to be 0.02 mg/L.