Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 228-762-1 | CAS number: 6358-09-4
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
The adsorption coefficient, Koc of the 2-amino-6-chloro-4-nitrophenol was 249 (log KOC: 2.40) measured by HPLC method (OECD 121).
Key value for chemical safety assessment
- Koc at 20 °C:
- 249
Additional information
The adsorption coefficient of the 2-amino-6-chloro-4-nitrophenol was determined under GLP and following methods comparable to the OECD 121 (Estimation of the Adsorption Coefficient (KOC) guideline on Soil and on Sewage Sludge) using High Performance Liquid Chromatography (HPLC)) .
The estimation of KOCof test material was conducted with a test material in mobile phase consisting of methanol and water in the ratio 55/45 (v/v). Samples of the test material were analyzed through HPLC on a cyanopropyl (CN-) column coupled with UV/V is detector (at 254 nm).
Calibration was performed using six reference materials with known values of log KOC, each with a nominal concentration of 1 mg/L in mobile phase. Dead time of the HPLC-system was determined to be 3.50 min. The column temperature was maintained at room temperature throughout the study.
The retention time of the test item was 5.69 min.The Adsorption Coefficient, KOCof 2-amino-6-chloro-4-nitrophenol deduced from the calibration curve was determined to be 249 (log KOC: 2.40).
This partition coefficient test is classified as acceptable, and satisfies the guideline requirements of the OECD 121 method.
[LogKoc: 2.4]
[LogKoc: 2.4]
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
