Registration Dossier
Registration Dossier
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EC number: 210-694-9 | CAS number: 621-59-0
Boiling point
Administrative data
Link to relevant study record(s)
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- August 29th, 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- method according to Siwoloboff
- Key result
- Boiling pt.:
- 304.7 °C
- Atm. press.:
- 1 013 hPa
- Decomposition:
- no
- Conclusions:
- The boiling point of the test item was observed at temperature of 304.7 ± 0.3 ºC, at 1013 hPa.
- Executive summary:
The determination of the boiling point of the test item was carried out according to EU method A.2 (method according to Siwoloboff) / OECD 103 (GLP study).The boiling point of the test item was observed at temperature of 304.7 ± 0.3 ºC, at 1013 hPa.
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Principles of method if other than guideline:
- Data from peer reviewed handbook. No information provided on methods.
- GLP compliance:
- not specified
- Type of method:
- other: not specified.
- Key result
- Boiling pt.:
- 179 °C
- Atm. press.:
- 15 mm Hg
- Conclusions:
- According to peer reviewed handbook data, isovanillin has a boiling point of 179ºC at 15 mmHg.
- Executive summary:
According to CRC Handbook of Chemistry and Physics, 96th ed. (peer reviewed), isovanillin has a boiling point of 179ºC at 15 mmHg (2000 Pa).
Referenceopen allclose all
Table 1. The observed values of the boiling point of the test item.
Sample |
The boiling point value, °C |
Atmospheric pressure, hPa |
1 |
304.7 |
1013 |
2 |
304.5 |
|
3 |
305.0 |
|
Average value ± standard deviation, °C |
304.7 ± 0.3 |
Description of key information
Key study. Method according to OECD 103 / EU method A.2, GLP study. The boiling point of the test item is 304.7 ± 0.3 °C (at 1013 hPa).
Key value for chemical safety assessment
- Boiling point at 101 325 Pa:
- 304.7 °C
Additional information
Key study. The determination of the boiling point of the test item was carried out according to EU method A.2 (method according to Siwoloboff) / OECD 103 (GLP study). The boiling point of the test item was observed at temperature of 304.7 ± 0.3 ºC, at 1013 hPa. Supporting data from a peer reviewed handbook reports the boiling point of the test item to be 179ºC at 15 mmHg (~2000 Pa).
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