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EC number: 273-662-3
CAS number: 68991-98-0
Pigment yellow 100 was studied for its
ability to induce mutations in strains of Salmonella typhimurium.
The test compound was dissolved in
DMSO and was tested at concentration of 0, 100, 333, 1000, 3333, 6666 or
10000 µg/plate using Salmonella typhimurium TA100, TA1535, TA1537, TA97
and TA98 in the presence and absence of 10 % and 30 % rat and hamster
liver S9 metabolic activation system. Preincubation assay was performed
with a preicubation for 20 mins. The plates were observed for histidine
independence after 2 days incubation period. Concurrent solvent and
positive controls were included in the study.
Pigment yellow 100 is not mutagenic to
the Salmonella typhimurium TA100, TA1535, TA1537, TA97 and TA98 in the
presence and absence of rat and hamster liver S9 metabolic activation
system and hence it is not likely to classify as a gene mutant in vitro.
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