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EC number: 205-851-3 | CAS number: 156-38-7
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Data is from modelling databases and Handbook
- Qualifier:
- according to guideline
- Guideline:
- other: refer principle below
- Principles of method if other than guideline:
- To determine partition coefficent of test chemical p-hydroxyphenylacetic acid (CAS no. 156-38-7)
- GLP compliance:
- not specified
- Type of method:
- other: no data available
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- - Name of test material: p-hydroxyphenylacetic acid
- IUPAC name: 4-Hydroxyphenylacetic Acid
- Molecular formula: C8H8O3
- Molecular weight: 152.148 g/mole
- Smiles : c1(ccc(O)cc1)CC(O)=O
- Inchl: 1S/C8H8O3/c9-7-3-1-6(2-4-7)5-8(10)11/h1-4,9H,5H2,(H,10,11)
- Substance type: Organic
- Physical state: Solid crystalline powder (off white) - Key result
- Type:
- log Pow
- Partition coefficient:
- 0.75
- Temp.:
- 25 °C
- Remarks on result:
- other: other details not available
- Conclusions:
- The octanol water partition coefficent log Pow of test chemical p-hydroxyphenylacetic acid (CAS no. 156-38-7) was determined to be 0.75 dimensionless. On the basis of this partition coefficient value it can be concluded that test chemical p-hydroxyphenylacetic acid (CAS no. 156-38-7) is hydrophilic in nature which is also supported by water solubility of test chemical.
- Executive summary:
The octanol water partition coefficent log Pow of test chemical p-hydroxyphenylacetic acid (CAS no. 156-38-7) was determined to be 0.75 dimensionless. On the basis of this partition coefficient value it can be concluded that test chemical p-hydroxyphenylacetic acid (CAS no. 156-38-7) is hydrophilic in nature which is also supported by water solubility of test chemical.
Reference
Description of key information
The octanol water partition coefficent log Pow of test chemical p-hydroxyphenylacetic acid (CAS no. 156-38-7) was determined to be 0.75 dimensionless. On the basis of this partition coefficient value it can be concluded that test chemical p-hydroxyphenylacetic acid (CAS no. 156-38-7) is hydrophilic in nature which is also supported by water solubility of test chemical.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 0.75
- at the temperature of:
- 25 °C
Additional information
The octanol water partition coefficent log Pow of test chemical p-hydroxyphenylacetic acid (CAS no. 156-38-7) was determined to be 0.75 dimensionless. On the basis of this partition coefficient value it can be concluded that test chemical p-hydroxyphenylacetic acid (CAS no. 156-38-7) is hydrophilic in nature which is also supported by water solubility of test chemical.
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