Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 215-403-9
CAS number: 1325-65-1
This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 40290.
Not skin sensitising.
shall be classified as skin sensitizers in category 1 where data are not
sufficient for sub-categorisation in accordance with the following
if there is evidence in humans that the substance can lead to
sensitisation by skin contact in a substantial number of persons; or
if there are positive results from an appropriate animal test.
for guinea pig maximisation test, a response of at least 30 % of animals
is considered positive.
Subcategorisation is done as follows in
case of a guinea pig maximisation test:
showing a high frequency of occurrence in humans and/or a high potency
in animals can be presumed to have the potential to produce significant
sensitisation in humans. Severity of reaction may also be considered.
Specific criteria: ≥ 30 % responding at ≤
0.1 % intradermal induction dose or ≥ 60 % responding at > 0.1 % to ≤ 1
% intradermal induction dose
showing a low to moderate frequency of occurrence in humans and/or a low
to moderate potency in animals can be presumed to have the potential to
produce sensitisation in humans. Severity of reaction may also be
criteria: ≥ 30 % to < 60 % responding at > 0.1 % to ≤ 1 % intradermal
induction dose or ≥ 30 % responding at > 1 % topical induction dose.
no positive response was seen in test animals upon a 5 % intradermal
induction dose, the substance is not classified within the CLP
Regulation (EC 1272/2008).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again