Registration Dossier
Registration Dossier
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EC number: 609-453-4 | CAS number: 37630-52-7
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- yes
- Remarks:
- The study plan states that the temperature during the test will not deviate more than +1ºC throughout the test, however, during the definitive test, the temperature ranged from 19 to 22 ºC. Although this was a deviation to the study plan, it was considere
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-Propenoic acid, 2-cyano-3-(3,4-dimethoxyphenyl)-, (2E)-
- EC Number:
- 609-453-4
- Cas Number:
- 37630-52-7
- Molecular formula:
- C12H11NO4
- IUPAC Name:
- 2-Propenoic acid, 2-cyano-3-(3,4-dimethoxyphenyl)-, (2E)-
- Test material form:
- solid: crystalline
Constituent 1
Results and discussion
Effect concentrations
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat. (dissolved fraction)
- Basis for effect:
- mobility
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The acute toxicity of the test item to the freshwater invertebrate Daphnia magna has been investigated and gave a 48-Hour EC50 value of greater than 100 mg/l. The No Observed Effect Concentration was 100 mg/l.
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