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EC number: 946-819-5 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (48 h, Daphnia magna) ≥ 4.90 mg/L (geom. mean of measured conc., corresponding to 100 mg/L nominal)
Key value for chemical safety assessment
Additional information
A static test was performed according to the OECD Guideline 202 (2004) and the EU method C.2 of the Regulation (EC) No. 440/2008. The study was performed using 5 concentrations ranging from 4.6 to 100 mg/L. For each test concentration and the blank control, 20 Daphnia were exposed to the test item for 48 hours in a static test system. After 24 and 48 hours, the immobilised Daphnia were counted.At the beginning and at the end of the test, the content of the test item in the test solutions was determined using aphotometricmethod. Potassium dichromate K2Cr2O7(CAS No. 7778-50-9) was used as positive controlin a current reference study to assure that the test conditions are reliable.
Three concentrations showed toxicity between 5 and 40 % immobilisation. None of the animals was immobilised in the blank control. The lowest treatment is not required for evaluation, as no immobilization has already occurred in the second lowest treatment. The recovery of the measured initial concentration (stability) is with 61 - 96% within the acceptable range.
Therefore the biological results were based on the geometric mean of the measured concentrations. The EC50 values are above the solubility limit and are therefore given as a range.
The following results were determined for the test item (species:Daphnia magna).
48h-NOEC
=1.8 mg/L (nominal 46 mg/L)
48h-LOEC = 4.90 mg/L (nominal 100 mg/L)
24h-EC50 > 4.90 mg/L (nominal 100 mg/L)
48h-EC50 > 4.90 mg/L (nominal 100 mg/L)
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