Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 246-677-8 | CAS number: 25155-23-1
Endpoint summary
Administrative data
Link to relevant study record(s)
- Endpoint:
- basic toxicokinetics
- Type of information:
- other: written assessment
- Adequacy of study:
- key study
- Study period:
- 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- A full toxicokinetic assessment of the substance is not deemed necessary. The toxicokinetic profile of this test substance has been addressed in a variety of studies since manufacture of the substance commenced in the 1950's, with detailed assessments throughout publically available literature being available. As such, it is deemed appropriate on animal welfare grounds to provide this as a written synopsis assessment only, rather than a definitive study. This is detailed below in "overall remarks".
Reference
Description of key information
Toxicokinetics, metabolism and distribution
Key value for chemical safety assessment
- Bioaccumulation potential:
- no bioaccumulation potential
- Absorption rate - oral (%):
- 100
- Absorption rate - dermal (%):
- 100
- Absorption rate - inhalation (%):
- 100
Additional information
A desktop assessment of Toxicokinetics, metabolism and distribution is undertaken. The substance is considered to be of low bioaccumulation potential.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
