Registration Dossier

Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
03 October 2017 - 13 October 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Cross-reference
Reason / purpose:
reference to same study
Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
03 October 2017 - 13 October 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
2008
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7200 (Melting Point / Melting Range)
Version / remarks:
1998
Deviations:
no
GLP compliance:
yes
Type of method:
differential scanning calorimetry
Key result
Melting / freezing pt.:
59.5 °C

TGA EXPERIMENT (PRELIMINARY TEST)

- 25% weight loss at 433°C

- 70% weight loss at 471°C

After the experiment, a black brown molten residue remained in the sample container (original colour: white). The change of the colour indicated reaction and/or decomposition of the test item.

DSC EXPERIMENT 1

An endothermic peak was observed between 25°C and 100°C. The endothermic effect was most likely caused by melting of the test item.The extrapolated onset temperature was 59.722°C. An exothermic peak was observed from 200°C. The exothermic effect was probably caused by reaction and/or decomposition of the test item. After the experiment, an orange molten residue remained in the sample container (original colour: white). The change of the colour indicated reaction and/or decomposition of the test item. 

DSC EXPERIMENT 2

In order to investigate the melting peak, a second experiment was performed and the end temperature was set to stop shortly after the melting peak. The extrapolated onset temperature was 59.319°C. After the experiment, a colourless molten residue remained in the sample container (original colour: white). It demonstrated that melting was the reason for the endothermic effect.

DATA HANDLING

The melting temperature was determined as the mean melting temperature of Experiment 1 (59.722°C) and Experiment 2 (59.319°C).

TGA and DSC curves are attached as background material.

Conclusions:
The melting temperature of the substance was determined to be 59.5°C (332.7 K).
Executive summary:

Differential Scanning Calorimetry (DSC) experiments were performed in a GLP study according to EC A.1, OECD 102 and OPPTS 830.7200.

The melting temperature of the substance was determined to be 59.5°C (332.7 K).

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report Date:
2017

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 103 (Boiling Point)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.2 (Boiling Temperature)
Version / remarks:
2008
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
Version / remarks:
1996
Deviations:
no
GLP compliance:
yes
Type of method:
differential scanning calorimetry

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Details on test material:
- Physical appearance: white powder with lumps
- Test item storage: at room temperature protected from light

Results and discussion

Boiling point
Key result
Decomposition:
yes
Decomp. temp.:
> 200 °C
Remarks on result:
other: no boiling point

Any other information on results incl. tables

TGA EXPERIMENT (PRELIMINARY TEST)

- 25% weight loss at 433°C

- 70% weight loss at471°C

After the experiment, a black brown molten residue remained in the sample container (original colour: white). The change of the colour indicated reaction and/or decomposition of the test item.

DSC EXPERIMENT 1

An exothermic peak was observed from 200°C. The exothermic effect was probably caused by reaction and/or decomposition of the test item.After the experiment, an orange molten residue remained in the sample container (original colour: white). The change of the colour indicated reaction and/or decomposition of the test item. 

CONCLUSION

Reaction and/or decomposition of the test itemwas observed during the DSC experiment at temperatures of > 200°C (> 473K). Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no boiling temperature.

TGA and DSC curves are attached as background material.

Applicant's summary and conclusion

Conclusions:
Reaction and/or decomposition of the substance was observed at temperatures > 200°C. Since boiling of the substance was not observed below the temperature at which reaction and/or decomposition started, it is concluded that the substance has no boiling temperature.
Executive summary:

Differential Scanning Calorimetry (DSC) experiments were performed in a GLP study according to EC A.2, OECD 103 and OPPTS 830.7220.

Reaction and/or decomposition of the substance was observed at temperatures > 200°C. Since boiling of the substance was not observed below the temperature at which reaction and/or decomposition started, it is concluded that the substance has no boiling temperature.