Registration Dossier

Ecotoxicological information

Toxicity to microorganisms

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study well documented, meets generally accepted scientific principles, acceptable for assessment.
Qualifier:
according to
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
Deviations:
yes
Remarks:
Sludge from a Husman laboratory apparatus
GLP compliance:
yes
Remarks:
Quality Assurance Certificate attached to the experimental report
Analytical monitoring:
yes
Vehicle:
yes
Details on test solutions:
Test concentration: 1; 3.2; 10; 32 and 100 mg/l
Test organisms (species):
activated sludge
Test type:
not specified
Water media type:
freshwater
Limit test:
no
Total exposure duration:
3 h
Reference substance (positive control):
yes
Remarks:
3,5 dichlorophenol (RIEDEL DE HAEN AG, No 62493)
Duration:
3 h
Dose descriptor:
IC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
not specified
Results with reference substance (positive control):
Positive control: 3,5- dichlorophenol
C50 positive results: 15 mg/l
Validity criteria fulfilled:
yes
Conclusions:
The tested substance apparead to be biodegradate by the active sludge based on the mass balance data.
Executive summary:

Based on the results of the test performed following OECD 209, the IC50 value is > 100 mg/l.

Description of key information

IC50 value is > 100 mg/l

Key value for chemical safety assessment

EC50 for microorganisms:
100 mg/L

Additional information