Registration Dossier
Registration Dossier
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EC number: 276-684-1 | CAS number: 72480-09-2
Endpoint summary
Administrative data
Description of key information
No readily biodegradable
Not bioaccumulable
Stable in air
Hydrolytically stable
Additional information
Based on the outcome of the OECD Guideline 111 (Hydrolysis as a Function of pH) test, the tested similar substance 01 is considered stable in air and hydrolytically stable.
The OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I)) and OECD Guideline 301 A (Ready Biodegradability: Modified AFNOR Test) were performed on the Similar substance 01. COD and BOD5 were also performed on the similar substance 01.
As conclusion, the Similar substance 01 showed no readily biodegradability.
Based on the read-across principle even the registered substance is considered hydrolytically stable and no ready biodegradable.
It can be assumed that the substance could have not a potential bioaccumulative and adsorption property on sediment and soil compartment.
Justification for read-across is detailed in the report attached to the IUCLID section 13.
The fate and behaviour of a chemical is largely governed by its inherent physico-chemical properties, As vapour pressure, water solubility, partition coefficient (HPLC method.
The sorption or binding behaviour of chemicals to sediment is determined by certain properties. Especially substances with high Log Kow or Log Koc values adsorb to the organic fraction of the sediment and soil.
In general substances with a Koc <500-1000 L/kg are not likely sorbed to sediments (SETAC 1993).
According to this, a log Koc or log Kow of >=3 is used as trigger value for sediment effect assessment although other concentration or combinations of triggers might be important as well (e.g. binding to sediment particles) that is not Kow/Koc driven, but where for instance the distribution coefficient Kd is important, persistence in the sediment compartment. Substances with a high potential to adsorb onto sediment (e.g. log Kow >5 or Log Koc >3) require sediment assessment even at tonnages below 1000 t/y.
Substances with tonnages below 1000 t/y and a not having a high potential for adsorption (e.g.log Kow <5 or log Koc <3)do not normally need a sediment risk assessment.
The same triggers as for parent compounds (e.g. log Koc >3) can be applied to degradation products.
If it is foreseeable that degradation products accumulate in the sediment or soil compartment, testing of degradation products might be necessary. Results from biodegradability test on similar substance indicates non biodegradability in water.
The substance under evaluation is not readily biodegradable, therefore no degradation products are expected in water compartment, and their accumulation in sediments and soil.
An experimental Kow that can be evaluated, being compared to the >=3 trigger value. The Log Pow experimental, based on the OECD Guideline 117 was stated at 1.96.
Furthermore, the substance has a high solubility (51.48g/L).
As conclusion, it can be assumed that the substance has not a potential adsorption property on sediment and soil compartments.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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