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EC number: 700-204-6
CAS number: 1174627-68-9
Number of nodes
10% in AOO
25% in AOO
50% in AOO
BG = Background (1 ml
5% trichloroacetic acid)
NC = Negative Control
Group (acetone/olive oil 4:1)
PC = Positive Control
Group (25%HCA in
The test item DV-SOLV
1059 was assessed in this study for its contact allergenic potential.
A local lymph node
assay was performed in CBA/J@Rj mice using test item concentrations of
10, 25 and 50% in acetone:olive oil 4:1.
The animals did not
show any clinical signs during the course of the study and no cases of
mortality were observed. No local signs of irritation of the ear skin
In this study
Stimulation Indices (S.I.) of 1.7, 1.6 and 1.2 were determined with the
test item at concentrations of 10, 25 and 50% in AOO, respectively. The
validity of the assay was demonstrated from the positive control
in AOO, with S.I. of 9.4. The test item was not a skin sensitizer in
this assay under the described conditions.
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