Registration Dossier
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EC number: 236-039-7 | CAS number: 13114-72-2
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 05.05.2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: isothermal thermogravimetry
- Key result
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Conclusions:
- The isothermal thermogravimetric effusion method was chosen for the determination of the vapour pressure of Akardit. The vapour pressure of the test item was determined below the melting point and at 20 °C (293.15 K) was:7.49 × 10-6 Pa (mean of three determinations).
- Executive summary:
The isothermal thermogravimetric effusion method was applied for the determination of the vapour pressure of Akardit. According to Sponsor information the melting point of the test item Akardit is 171 °C. Therefore, the evaluation of the measurement was done below the melting point. A value of the vapour pressure of the test item was determined using the data obtained between 110 °C and 140 °C. The vapour pressure of the test item at 20 °C (293.15 K) was calculated to: 7.49 × 10-6 Pa (mean of three determinations).
Reference
Description of key information
The isothermal thermogravimetric effusion method was applied for the determination of the vapour pressure of Akardit.
This study was based on the procedures indicated by the following internationally accepted methods:
− European Community (EC), EC no. 761/2009, Part A: Methods for the Determination of Physico-Chemical Properties, Guideline A.4: “Vapour Pressure", Official Journal of the European Union No. L220, August 24, 2009.
− Organisation for Economic Co-operation and Development (OECD), OECD Guidelines for the Testing of Chemicals No. 104: "Vapour Pressure", March 23, 2006.
Only one study is available.
GLP study.
Klimish score 1.
The vapour pressure of the test item at 20 °C (293.15 K) was calculated to: 7.49 × 10-6 Pa (mean of three determinations).
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 20 °C
Additional information
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