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Diss Factsheets
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EC number: 204-171-4 | CAS number: 117-08-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxicity to fish (Oryzias latipes) was measured during 96 hours and showed a LC50 >106 mg/L. The substance does not to be classified based on the result of this study in accordance with the criteria set in Directive 67/548/EC and Regulation (EC) 1272/2008 including the Regulation (EC) 286/2011.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 106 mg/L
Additional information
No assignable toxicity tests to fish using tetrachlorophthalic anhydride as test substance are available.
As tetrachlorophthalic anhydride hydrolysis rapidly in water forming the the hydrolysis product tetrachlorophthalic acid (CAS , tests with tetrachlorophthalic acid are used to draw a conculsionon toxicity to fish.
At the National Institute of Technology and Evaluation, Japan, acute toxicity to fish (Oryzias latipes) with tetrachlorophthalic acid as test substance was determined according to the OECD TG 203. Tetrachlorophthalic acid was exposed to a test solution of a nominal test substance concentration of 100 mg/L and to a blank control solution for a period of 96 h under semi static conditions in buffered medium. Mobility and visible abnormalities were recorded at 24, 48, 72 and 96 h. The mesured concentrations confirmed that deviation from the nominal concenntrations was less than 20 % (measured concentrations were range of 80 - 102.2 % of nominal concentrations). No toxic effect and abnormal behavior were observed. This toxicity study is classified as acceptable and satisfies the guideline requirements for the acute fish study.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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