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EC number: 946-382-0
CAS number: -
An acute dermal toxicity test was conducted according to OECD/ EC
guidelines and GLP principles with PEMP. Five male and five female rats
were semi-occlusively exposed for 24 hours to 2000 mg/kg bw. No
mortality occurred, no clinical signs were noted. Three females were
found to have adverse skin reactions, including haemorrhage of the
dermal capillaries, moderate erythema, keratolysis (glossy skin), small
superficial scattered scabs and desquamation. The skin of these treated
animals appeared normal 7 days after treatment.
Based on these data, the dermal LD50 for PEMP was determined to exceed
2000 mg/kg bw, therefore the substance is not classified for dermal
toxicity according to Regulation (EC) 1272/2008.
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