Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 946-382-0
CAS number: -
An acute dermal toxicity test was conducted according to OECD/ EC
guidelines and GLP principles with PEMP. Five male and five female rats
were semi-occlusively exposed for 24 hours to 2000 mg/kg bw. No
mortality occurred, no clinical signs were noted. Three females were
found to have adverse skin reactions, including haemorrhage of the
dermal capillaries, moderate erythema, keratolysis (glossy skin), small
superficial scattered scabs and desquamation. The skin of these treated
animals appeared normal 7 days after treatment.
Based on these data, the dermal LD50 for PEMP was determined to exceed
2000 mg/kg bw, therefore the substance is not classified for dermal
toxicity according to Regulation (EC) 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again