Registration Dossier

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
publication
Title:
Drugs in Japan Vol. -, Pg. 156
Year:
1995
Bibliographic source:
https://chem.nlm.nih.gov/chemidplus

Materials and methods

Principles of method if other than guideline:
Method not available
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Inosine
EC Number:
200-390-4
EC Name:
Inosine
Cas Number:
58-63-9
Molecular formula:
C10H12N4O5
IUPAC Name:
inosine
Test material form:
solid: particulate/powder

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
> 10 000 mg/kg bw

Applicant's summary and conclusion