Registration Dossier

Administrative data

Description of key information

Study was scientifically not necessary for testing of this end point since pH of (3-aminopropyl)(methyl)amine (CAS No: 6291-84-5) was determined to be in 13.5 (From GESTIS), indicating that it was corrosive to skin hence the end point was considered for waiver.

Key value for chemical safety assessment

Skin sensitisation

Link to relevant study records
Reference
Endpoint:
skin sensitisation: in vivo (non-LLNA)
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance is a strong acid (pH ≤2.0) or base (pH =>11.5)
Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

Study was scientifically not necessary for testing of this end point since pH of (3-aminopropyl)(methyl)amine (CAS No: 6291-84-5) was determined to be in 13.5 (From GESTIS), indicating that it was corrosive to skin hence the end point was considered for waiver.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

Study was scientifically not necessary for testing of this end point since pH of (3-aminopropyl)(methyl)amine (CAS No: 6291-84-5) was determined to be in 13.5 (From GESTIS), indicating that it was corrosive to skin hence the end point was considered for waiver.