Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: -
CAS number: -
Table 1. Individual ocular response in one rabbit following
administration of TOFA_DimerFA_TETA_PAA
Time after treatment
Individual ocular response – male rabbit
* = fluorescein applied to cornea
The eye irritant potential of TOFA_DimerFA_TETA_PAA was evaluated in a
single, male New Zealand White rabbit according to OECD 405. The
undiluted test material (0.1 mL) was instilled into the left
conjunctival sac of the rabbit on Day 1, the right eye remained
untreated to serve as the control. Ocular reactions were assessed
according to the Draize scoring system for 21 days after administration.
Instillation of the test material produced easily discernible
translucent areas of corneal opacity, iridial inflammation and severe
conjunctival irritation. The effects on the cornea, iris and conjunctiva
did not reverse within the 21 - day observation period therefore the
test material was considered to be corrosive.
Based on the results of this study, the test material is classified as
causing irreversible effects on the eye (Category 1) according to
Regulation (EC) No 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again