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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Biodegradation in water

Biodegradability of 2-Propen-1-yl butanoate (CAS no. 2051 -78 -7) is predicted using OECD QSAR toolbox version 3.3 (2017) with logKow as the primary descriptor. Test substance undergoes 89.6% degradation by BOD in 28 days. Thus, based on percentage degradation, the test chemical 2-Propen-1-yl butanoate was estimated to be not readily biodegradable in water.

Biodegradation in water & sediment

Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound 2-Propen-1-yl butanoate (CAS No. 2051 -78 -7). If released in to the environment, 36.4% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of 2-Propen-1-yl butanoate in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of 2-Propen-1-yl butanoate in sediment is estimated to be 135 days (3240 hrs). However, as the percentage release of test chemical into the sediment is less than 1% (i.e, reported as 0.12%), indicates that 2-Propen-1-yl butanoate is not persistent in sediment.

 

Biodegradation in soil

The half-life period of 2-Propen-1-yl butanoate (CAS No. 2051 -78 -7) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 61.2% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of 2-Propen-1-yl butanoate in soil is estimated to be 30 days (720 hrs). Based on this half-life value of 2-Propen-1-yl butanoate, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low.

Additional information

Biodegradation in water

Various predicted data for the target compound 2-Propen-1-yl butanoate (CAS No. 2051-78-7) and supporting weight of evidence studies for its read across substance were reviewed for the biodegradation end point which are summarized as below:

 

In a predicted data done by SSS (2017) using OECD QSAR toolbox version 3.3 with logKow as the primary descriptor, percentage biodegradability of test chemical2-Propen-1-yl butanoate(CAS No. 2051-78-7) was estimated.Test substance undergoes 89.6% degradation by BOD in 28 days. Thus, based on percentage degradation, the test chemical 2-Propen-1-yl butanoate was estimated to be not readily biodegradable in water.

 

In another prediction using the Estimation Programs Interface Suite (EPI suite, 2017), the biodegradation potential of the test compound 2-Propen-1-yl butanoate (CAS No. 2051-78-7) in the presence of mixed populations of environmental microorganisms was estimated.The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that chemical 2-Propen-1-yl butanoate is expected to be readily biodegradable.

 

In a supporting weight of evidence study from peer reviewed journal (A.M. Api, et. al; 2017), biodegradation experiment was conducted for 28 days for evaluating the percentage biodegradability of read across substance 3-Methylbutyl propanoate (CAS no. 105-68-0). The study was performed according to OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test).The percentage degradation of read across substance 3-Methylbutyl propanoate was determined to be 74% by O2 consumption parameter in 28 days. Thus, based on percentage degradation, 3-Methylbutyl propanoate is considered to be readily biodegradable in nature.

 

Another biodegradation study was conducted for 20 days for evaluating the percentage biodegradability of read across substance 2-methyl propyl acetate (CAS no. 110-19-0) (Kenneth S. Price, et. al; 1974). Initial test substance conc. used in the study was 3, 7 and 10 mg/l, respectively. Domestic wastewater was used as a test inoculum. The BOD bottles were half filled with aerated dilution water containing the specified minerals and buffer. Small aliquots of the test chemicals were added to these bottles from 0.1% stock solutions yielding conc. of 3, 7 and 10 mg/l. At least two of these concentrations were tested in duplicate. These concentrations gave a potential oxygen demand of 3 to 30 mg/l over the 20 days duration of test. Dissolved oxygen was monitored periodically in the individual bottles through the use of a commercial DO meter filled with an agitated probe. The bottles were opened for sampling and DO measurements about five times during the course of the 20 day test. The percentage degradation of substance 2-methyl propyl acetate was determined to be 60, 74, 79 and 81% in 5, 10, 15 and 20 days, respectively. Thus, based on percentage degradation, 2-methyl propyl acetate is considered to be readily biodegradable in nature.

 

For theread across substance 2-methyl-2-propenoic acid 2-propenyl ester (CAS no. 96-05-9) from authoritative database (J-CHECK and HSDB, 2017), biodegradation experiment was conducted for 14 days for evaluating the percentage biodegradability of read across substance 2-methyl-2-propenoic acid 2-propenyl ester. The study was performed according to OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I)) under aerobic conditions. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of substance 2-methyl-2-propenoic acid 2-propenyl ester was determined to be 62, 95 and 100% by BOD, TOC removal and HPLC parameter in 14 days. Thus, based on percentage degradation, 2-methyl-2-propenoic acid 2-propenyl ester is considered to be readily biodegradable in nature.

 

In a supporting weight of evidence study from authoritative database (HSDB, 2017) for the read across chemical 2-Propenoic acid, 2-methyl-, ethyl ester (CAS no. 97-63-2), biodegradation experiment was conducted for 28 days for evaluating the percentage biodegradability of read across substance 2-Propenoic acid, 2-methyl-, ethyl ester. The study was performed according to OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test) under aerobic conditions. The percentage degradation of substance 2 -Propenoic acid, 2 -methyl-, ethyl ester was determined to be 79% by O2 consumption parameter in 28 days. Thus, based on percentage degradation, 2 -Propenoic acid, 2 -methyl-, ethyl ester is considered to be readily biodegradable in nature.

 

On the basis of above results for target chemical 2-Propen-1-yl butanoate (from OECD QSAR toolbox version 3.3 and EPI suite, 2017) and for its read across substance (from authoritative database J-CHECK, HSDB and peer reviewed journals), it can be concluded that the test substance 2 -Propen-1 -yl butanoate can be expected to be readily biodegradable in nature.

Biodegradation in water & sediment

Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound 2-Propen-1-yl butanoate (CAS No. 2051 -78 -7). If released in to the environment, 36.4% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of 2-Propen-1-yl butanoate in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of 2-Propen-1-yl butanoate in sediment is estimated to be 135 days (3240 hrs). However, as the percentage release of test chemical into the sediment is less than 1% (i.e, reported as 0.12%), indicates that 2-Propen-1-yl butanoate is not persistent in sediment.

 

Biodegradation in soil

The half-life period of 2-Propen-1-yl butanoate (CAS No. 2051 -78 -7) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 61.2% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of 2-Propen-1-yl butanoate in soil is estimated to be 30 days (720 hrs). Based on this half-life value of 2-Propen-1-yl butanoate, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low.

On the basis of available information, the test substance 2 -Propen-1 -yl butanoate can be considered to be readily biodegradable in nature.