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EC number: -
CAS number: -
Individual body weights and body weight changes:
Dose level mg/kg
Animal number and sex
Body weight (g) at Day
Body weight gain (g) during week
Guideline 420 and EC Method B.1 bis (Acute Oral Toxicity - Fixed Dose
sighting study at the dose level of 2000 mg/kg bw, an addition 4 fasted
Wistar rats (RccHan™:WIST) were given a single oral (gavage) dose of the
test material at 2000 mg/kg bw. Animals were then observed for
mortality, clinical signs and bodyweights for 14 days and were all
sacrificed for macroscopic examination.
mortality was observed. No signs of systemic toxicity were noted during
the observation period. All animals showed expected gains in body weight
over the observation period. No abnormalities were observed at necropsy.
In this study, the oral LD50 of the test item was considered to be
higher than 2000 mg/kg bw in female rats.
the test conditions, the oral meadian LD50 is higher than 2000 mg/kg bw
in female rats, therefore the substance is not classified according to
CLP Regulation (EC) No. 1272 /2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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