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EC number: -
CAS number: -
The potential for the test material to bioaccumulate was evaluated in a
study conducted in accordance with the Test Method Relating to New
Chemical Substances “Bioconcentration test of chemical substances in
fish and shellfish” (Japanese notification, Yakushokuhatsu 0331 No.7,
Heisei 23.03.29 Seikyoku No.5, Kanpokihatsu No.110331009, March 31,
2011; latest revision, December 21, 2015). Carp were exposed to
concentrations up to 1 mg/L for 61 days in a flow-through study. Due to
a lack of analytical sensitivity, BCF could not be confirmed to be less
than 1000 L/kg in any component at the low concentration level.
Meanwhile, BCFs of all components at the high concentration level were
below 489 L/kg, BCFs of all components at the low concentration level
were less than 1400 L/kg, and no components detected. Therefore, it can
be concluded that the bioconcentration potential of the test substance
in fish is not high.
Abiotic degradation; Hydrolysis
Since the test item is a complex mixture
and has low solubility in aqueous media, and in accordance with REACH
Annex VIII, Section 220.127.116.11, column 2, assessment of hydrolytic
stability was not carried out using Method C.7 Abiotic degradation,
Hydrolysis as a Function of pH of Commission Regulation (EC) No 440/2008
of 30 May 2008 and Method 111 of the Guidelines for Testing of
Chemicals, 13 April 2004.
In a key study performed to OECD Guideline
301B, EC Method C.4 -C and US EPA OPPTS 835.3110, the test item at a
concentration of 10 mg C/L was exposed to activated sewage sludge
micro-organisms with a mineral medium in sealed culture vessels in the
dark at 20 to 22°C for 28 days. The degradation of the test item was
assessed by the determination of carbon dioxide produced. Control
solutions with inoculum and the reference item, sodium benzoate,
together with a toxicity control were used for validation purposes. The
test item attained 16% degradation after 28 days. The test item cannot
therefore be considered to be readily biodegradable under the terms and
conditions of the Guideline.
Adsorption / desorption coefficient
In a key study using the HPLC screening
method designed to be compatible with Method C.19 of Commission
Regulation (EC) No 440/2008 of 30 May 2008 and Method 121 of the OECD
Guidelines for Testing of Chemicals, 22 January 2001, the
adsorption coefficient of the test item was determined to be greater
than 4.27 x 10E5 with a log10 Koc of > 5.63.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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