Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

The guideline conform local lymph node assay with the test substance showed a clear negative result indicating that the test substance was not sensitizing in this assay.


Migrated from Short description of key information:
A guidleine confrom local lymph node assay in mice was performed under GLP conditions and did not reveal any skin sensitizing properties of the substance.

Respiratory sensitisation

Endpoint conclusion
Additional information:

No data are available and no observations have been made that would cause any concern of a possible respiratory senistization. In the absence of skin sensitization it can be concluded that the test substance is unlikely to cause respiratory sensitization.


Migrated from Short description of key information:
No data are available and no observations have been made that would cause any concern of a possible respiratory senistization. In the absence of skin sensitization it can be concluded that the test substance is unlikely to cause respiratory sensitization.

Justification for classification or non-classification

Due to the negative results for skin sensitization in a guideline conform local lymph node assay the substance is not classified for skin sensitization.

No data are available and no observations have been made that would cause any concern of a possible respiratory senistization. In the absence of skin sensitization it can be concluded that the test substance is unlikely to cause respiratory sensitization.