Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
August 3, 2016 - August 11, 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report Date:
2016

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
yes
Remarks:
Solubility is below 10-2 g/l, so the column elution method should be applied according to the guideline. Therefore the flask method was applied.
GLP compliance:
yes (incl. certificate)
Type of method:
flask method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
impurity
Test material form:
solid: particulate/powder
Details on test material:
Batch No.: 2016JAN-15kg
Expiry Date: 01 January 2020
Appearance: Blue-white powder
Storage: Room temperature (15-25°C)
Safety precautions: Routine safety precautions (lab coat, gloves, safety glasses, face mask) for unknown materials were applied to assure personnel health and safety.
Specific details on test material used for the study:
Batch No.: 2016JAN-15kg
Expiry Date: 01 January 2020
Appearance: Blue-white powder
Storage: Room temperature (15-25°C)

Results and discussion

Water solubility
Key result
Water solubility:
0.12 mg/L
Conc. based on:
test mat.
Loading of aqueous phase:
0.05 mg/L
Incubation duration:
24 - 72 h
Temp.:
30 °C
pH:
5.7

Applicant's summary and conclusion

Conclusions:
Water solubility of Neodymium fluoride oxide, magnesium doped was determined to be 0.12 mg/L at 20 °C.
Executive summary:

In the course of this study water solubility of Neodymium fluoride oxide, magnesium doped was investigated using the shake flask method. Water solubility was calculated based on the neodymium concentration measured in water by a previously validated ICP-OES method. Water solubility of Neodymium fluoride oxide, magnesium doped was determined to be 0.12 mg/L at 20 °C.