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Sediment toxicity

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The need for toxicity testing information on sediment organisms is waived. The use of SPE1415 in offshore drilling operations means that exposure to the freshwater environment is extremely unlikely. SPE1415 is used in the marine environment, although the substance is not expected to be transported to the sediment compartment. The Log10KOC of SPE1415 was determined experimentally to be <1.25, indicating that SPE1415 is expected to be mobile and is not expected to adsorb to sediment. This is supported by the result of the experimentally derived LogKOW partition coefficient, which was estimated to be less than -2, indicating the test substance is not expected to be taken up and accumulated by sediment biota. In addition, the test requires the use of suitably radiolabelled substance or detailed knowledge of the fate of the substance in water and sediment. As a complex UVCB, conducting such a test would be technically unfeasible.

In addition, two supporting studies are available for the analogue substances ATMP and DTPMP used in read-across argumentations for SPE1415. In the study by Bowmer et al (1997), a 10 day LC50 value of >2,910 mg active acid/kg dw was determined for the effects of the test substance ATMP on the mortality of the marine sediment-dwelling organism Corophium sp. In a reliable study by the TNO Institute (1997) a 10 day LC50 value of >2500 mg active acid/kg dw sediment was determined for the effects of DTPMP-xNa on the mortality of the marine sediment ostracod Corophorium spp. These two studies demonstrate that the read-across analogue substances ATMP and DTPMP have very low acute toxicities to sediment organisms and were not toxic at the high concentrations tested. Based on the argumentations presented in the Read-Across Report for these analogue substances, it is unlikely that the test substance SPE1415 is toxic to sediment organisms.

This endpoint is waived on the basis of the targeted use of the test substance (offshore marine environment), the unlikely potential for acute toxicity to sediment organisms and the unlikely potential for exposure to sediment organisms due to the unlikely potential for the test substance to adsorb to sediments.

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