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Environmental fate & pathways

Adsorption / desorption

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Reference
Endpoint:
adsorption / desorption: screening
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
Qualifier:
according to
Guideline:
EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC estimation method
Radiolabelling:
no
Test temperature:
30 degrees centigrade
Details on study design: HPLC method:
HPLC System: Agilent Technologies 1100 Series
Column: XSelect HSS Cyano 5 μm (150 x 4.6 mm id)
Column temperature: 30ºC
Mobile phase: Methanol: Purified water (55:45 v/v)
pH of mobile phase: 6.2
Flow-rate: 1.0 mL/min
Injection volume: 10 μL
UV detector wavelength: 210 nm
Substance for dead time: Formamide (654 mg/L in mobile phase)
Dead time: 1.892 minutes
Key result
Type:
Koc
Value:
< 17.8
Temp.:
30 °C
Key result
Type:
log Koc
Value:
< 1.25
Temp.:
30 °C
Details on results (HPLC method):
Reference substance retention times are detailed in any other information section below

Partition coefficient (HPLC method)

Dead time to / min:

No.

Reference substance

Retention time (min)

log k value

log Koc value

1

Acetanilide

2.599

-0.428

1.25

2

Phenol

2.473

-0.513

1.32

3

Atrazine

3.596

-4.56 x 10-2

1.81

4

Isoproturon

3.841

1.28 x 10-2

1.86

5

Aniline

2.729

-0.354

2.07

6

Triadimenol

5.118

0.232

2.40

7

Linuron

5.255

0.250

2.59

8

Naphthalene

4.548

0.147

2.75

9

Endosulfan-Diol

6.466

0.383

3.02

10

Fenthion

7.783

0.493

3.31

11

a-Endosulfan

10.959

0.680

4.09

12

Diclofop-Methyl

11.824

0.720

4.20

13

Phenanthrene

8.454

0.540

4.09

14

DDT

23.259

1.05

5.63

TS1

SPE1415

1.411

<-0.428

<1.25

Validity criteria fulfilled:
yes
Conclusions:
The adsorption coefficient (Koc) of the substance is less than 17.8, log10Koc less than 1.25. These values indicate that the test item will have a very high mobility in the environment.
Executive summary:

The adsorption coefficient (Koc) of SPE1415 was determined according to OECD Guideline for the Testing of Chemicals No. 121 “Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC)”, adopted 22 January 2001. The test method was designed to be compatible with Method C19 “Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using high Performance Liquid Chromatography (HPLC)”

The Kocwas estimated to be <1.25 (highest standard) and the adsorption coefficient was <17.78. These values demonstrate that SPE1415 will have a very high mobility in the environment.

Reference substances (and respective log Kocvalues) were: Acetanilide (1.25), Phenol (1.32), Atrazine (1.81), Isoproturon (1.86), Aniline (2.07), Triadimenol (2.40), Linuron (2.59), Naphthalene (2.75), Endosulfan-Diol (3.02), Fenthion (3.31),a-Endosulfan (4.09), Diclofop-Methyl (4.20), Penanthrene (4.09) and DDT (5.63).

The calibration showed a correlation of 0.903.

Description of key information

A reliable (Klimisch 1) study is available for the test item. The study was conducted according to GLP and following internationally accepted test guidelines.

The adsorption coefficient (Koc) of the substance is less than 17.8, log10Koc less than 1.25. These values indicate that the test item will have a very high mobility in the environment

Key value for chemical safety assessment

Koc at 20 °C:
17.8

Additional information

[LogKoc: 1.25]