Registration Dossier
Registration Dossier
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EC number: 201-744-0 | CAS number: 87-41-2
Toxicity to terrestrial plants
Administrative data
- Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Scientifically acceptable method
Data source
Reference
- Reference Type:
- publication
- Title:
- Comparative Effects of Heterocyclic Compounds on Inhibition of Lettuce Fruit Germination
- Author:
- Reynolds T
- Year:
- 1 989
- Bibliographic source:
- Journal of Experimental Botany 40 (212): 391-404.
Materials and methods
- Principles of method if other than guideline:
- - Fruit germination inhibition test according to Reynolds (1975)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Phthalide
- EC Number:
- 201-744-0
- EC Name:
- Phthalide
- Cas Number:
- 87-41-2
- Molecular formula:
- C8H6O2
- IUPAC Name:
- 1(3H)-Isobenzofuranone
- Details on test material:
- - Name of test material (as cited in study report): Phthalide
- Analytical purity: not reported
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test substrate
- Vehicle:
- not specified
Test organisms
- Species:
- Lactuca sativa
- Plant group:
- Dicotyledonae (dicots)
Study design
- Test type:
- seedling emergence toxicity test
- Study type:
- laboratory study
- Substrate type:
- other: agar (0.5%)
- Total exposure duration:
- 3 d
Test conditions
- Test temperature:
- 30 °C
- Details on test conditions:
- TEST SYSTEM
- Testing facility:
- Test container (type, material, size): Plastic containers sealed with snap-on lids
- Number of replicates: 5
Results and discussion
Effect concentrationsopen allclose all
- Species:
- Lactuca sativa
- Duration:
- 3 d
- Dose descriptor:
- EC50
- Effect conc.:
- 14.8 other: mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- germination
- Species:
- Lactuca sativa
- Duration:
- 3 d
- Dose descriptor:
- EC50
- Effect conc.:
- 22.2 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- germination
Any other information on results incl. tables
In addition the EC50 -value was converted to mg/kg soil dw. Since the amount of agar in the test was with 0.5% negligiable, the EC50 of 14.8 mg/L was related to mg/kg water and multiplicated with the factor of 1.5 (standard soil density) to get mg/kg soil dw.
Applicant's summary and conclusion
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