Registration Dossier
Registration Dossier
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EC number: 200-891-8 | CAS number: 75-68-3
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Aquatic toxicity testing with gases often lead to invalid results because of the technical difficulties associated with the physical state of the substances. Commercially available HFCs and HCFCs share common physicochemical and environmental fate. Although it is not possible to identify clear structure-related trends along the series, the common features present in the ecotoxicological profiles of these substances demonstrate that category approach is justified for these two groups of substances.
That is the reason why we proposed to use category approach and fill the missing data by using QSARs data and/or read-across. Besides, the exposition of the aquatic compartment will be very low based upon the volatility of the considered substances. In other words, fluorocarbons will partition in the atmospheric compartment very quickly. In other words, the aquatic compartment is not the final environmental compartment of the concerned substances. Last but not the least, in this approach we use each time the most conservative approach in order to fill the missing data with data that would’ not underestimate the hazard for the aquatic compartment.
Conclusion on classification
Initial EU and GHS hazard classification
Based on all available ecotoxicological data for daphnids, fish and algae, 1-chloro-1,1-difluoroethane need to be labelled R52/53 according to Directive 67/548/EEC as the lowest acute toxicity value is 96.6 mg/l. 1-chloro-1,1-difluoroethaneF is not readily biodegradable. Furthermore, as the substance has a very low log Kow of 2.05 the substance is not expected to be bioaccumulative. According to EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008 difluoromethane need to be labelled Aquatic chronic toxicity category 3.
Preliminary PBT assessment
An assessment of the PBT status of difluoromethane has been made using all available data. The information available suggests that HFC 142b does not meet the PBT screening criteria as outlined in Directive 2006/121/EC.
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