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EC number: 202-616-7
CAS number: 97-89-2
The SD value for CAS 97-89-2 is SD >18.
The dermal irritation potential of test
article was determined according to the OECD 439. In Vitro Skin
Irritation: Reconstructed Human Epidermis Test Method”. The MatTek
EpiDerm™ model was used to assess the potential dermal irritation of the
test article by determining the viability of the tissues following
exposure to the test article via MTT. The objective of this study was to
assess the dermal irritation potential of test article Tissues were
exposed to test article and controls for ~one hour, followed by a 42
hour post-exposure recovery period. The viability of each tissue was
determined by MTT assay. The MTT data shows that
the assay quality controls were met. The mean tissue viabilities for the
Positive control, Methyl acetate were 6.5%, 10.7% respectively in the
first and second run, whereas the tissue viabilities of the negative
control, Tissue culture water remained at 100% in the both the runs. The
Mean % tissue viability compared to negative control (n=3) of the test
substance was determined to be 79.3 %. Thus, the test substance was
considered to be not irritating to the human skin.
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