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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline study. Basic data given.

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
A QSAR study of the toxicity of nitrobenzene derivatives towards Daphnia magna, Chlorella pyrenoidosa and Photobacterium phosphoreum
Author:
Deneer JW, van Leeuwen CJ, Seinen W, Maas-Diepeveen JL, Hermens JLM
Year:
1989
Bibliographic source:
Aquatic Toxicology 15: 83-98
Reference Type:
secondary source
Title:
1,2-Dichlornitrobenzole (1,2-Dichlor-3-nitrobenzol, 1,2-Dichlor-4-nitrobenzol)
Author:
BUA (Beratergremium umweltrelevanter Altstoffe) (BUA)
Year:
1990
Bibliographic source:
Gesellschaft Deutscher Chemiker (Hrsg Behret) Bd 52, VCH (Verlag Chemie), Weinheim
Reference Type:
publication
Title:
Parametric analysis of population growth in bio-assays.
Author:
Kooyman SALM, Hanstveit AO, Oldersma H
Year:
1983
Bibliographic source:
Water Res. 17, 527-538
Reference Type:
publication
Title:
Aquatic Toxicological Aspects of Dithiocarbamates and related Compounds. I. Short-term Toxicity Tests
Author:
van Leeuwen CJ, Maas-Diepeveen JL, Niebeek G, Vergouw WHA, Griffioen PS, Luijken MW
Year:
1985
Bibliographic source:
Aquatic Toxicology 7: 145-164

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
Version / remarks:
, 1984
Deviations:
yes
Remarks:
: slight modifications according to Van Leeuwen et al., 1985
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): 2,3-Dichloronitrobenzene
- Analytical purity: not given

Sampling and analysis

Analytical monitoring:
not specified

Test organisms

Test organisms (species):
Chlorella pyrenoidosa

Study design

Water media type:
freshwater
Total exposure duration:
96 h

Test conditions

Nominal and measured concentrations:
Test concentrations increased geometrically with a factor of 3.2.

Results and discussion

Effect concentrations
Duration:
96 h
Dose descriptor:
EC50
Effect conc.:
2.9 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
biomass

Any other information on results incl. tables

- the result published in the paper is log EC50 = 1.18 µmol/l

- the result mentioned above was calculated by the applicant based on the reported log IC50

Applicant's summary and conclusion

Executive summary:

Deneer et al.(1989) determined the effect of 2,3-dichloronitrobenzene on the population growth of Chlorella pyrenoidosa, as described in the OECD guideline 201 (1984), including some slight modifications indicated elsewhere (van Leeuwenet al., 1985). The 96h-log EC50 was 1.18 µmol/l corresponding to an EC50 of 2.9 mg/l.