Registration Dossier
Registration Dossier
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EC number: 436-710-6 | CAS number: 756-13-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Exposure of Pseudokirchneriella subcapitata to CAS# 756-13-8 resulted in 72 and 96 hour EC50s (based on average specific growth rate) that were greater than the nominal loading rate.
CAS# 756-13-8 was added to the stock solutions at 150 mg/L, which is in excess of water solubility. The dissolved material hydrolyzed completely with a half life of less than 2.5 minutes to water-soluble perfluoropropionic acid (PFPA) and a volatile hydrofluorocarbon (heptafluoropropane). PFPA was quantified at 6.78 mg/L in the stock solution. This concentration of perfluoropropionic acid caused a decrease in average specific growth rate and number of cells per milliliter, but did not cause any size differences, unusual cell shapes, colors, flocculations, adherence to test containers, or aggregations. The 72-hour and 96-hour EC50s based on average specific growth rate were >6.78 mg/L as PFPA. The 96-hour NOEC based on average specific growth rate was 3.47 mg/L as PFPA.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 6.78 mg/L
- EC10 or NOEC for freshwater algae:
- 3.47 mg/L
Additional information
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