Registration Dossier
Registration Dossier
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EC number: 202-809-6 | CAS number: 100-00-5
Biodegradation in water and sediment: simulation tests
Administrative data
- Endpoint:
- biodegradation in water and sediment: simulation tests
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: study with acceptable limitations
Data source
Reference
- Title:
- No information
- Author:
- Corbett, M. D. and Corbett, B. R., Metabolism of 4-Chloronitrobenzene by the Yeast Rhodosporidium sp., Applied and Environmental Microbiology 41, 942-949 (1981)
Materials and methods
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1-chloro-4-nitrobenzene
- EC Number:
- 202-809-6
- EC Name:
- 1-chloro-4-nitrobenzene
- Cas Number:
- 100-00-5
- Molecular formula:
- C6H4ClNO2
- IUPAC Name:
- 1-chloro-4-nitrobenzene
- Details on test material:
- Test substance: no data
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: other fungi: Rhodosporidium sp.
- Duration of test (contact time):
- 14 d
Initial test substance concentration
- Initial conc.:
- 0.1 mmol/L
- Based on:
- test mat.
Results and discussion
% Degradation
- % Degr.:
- > 90
- Sampling time:
- 10 d
- Transformation products:
- yes
- Details on results:
- Degradation products (CAS No./EC No./EINECS Name): 4-chloro-2-hydroxyacetanilide
Degradation products (CAS No./EC No./EINECS Name): 106-47-8 203-401-0 4-chloroaniline
Degradation products (CAS No./EC No./EINECS Name): 539-03-7 208-707-8 4'-chloroacetanilide
Degradation products (CAS No./EC No./EINECS Name): 932-98-9 213-263-3 4-chloronitrosobenzene
Any other information on results incl. tables
2 degradation routes postulated after analysis of metabolic products. Major final metabolites are 4-chloroacetanilide and 4-chloro-2-hydroxyacetanilide.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results: other: biotic reduction
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