Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP guideline study without anayltical monitoring

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1998
Report Date:
1998

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: German industrial standard test guideline DIN 38412, part 11
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Cyanethylimidazol
- Analytical purity: >95%

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Daphnia magna
Details on test organisms:
TEST ORGANISM
- Common name: water flea
- Strain: STRAUS
- Source: The clone of Daphnia magna STRAUS used was supplied by Institut National de Recherche Chimique Appliquée, France, in 1978 . The daphnids are cultured under standard conditions in the laboratory .
- Age at study initiation (mean and range, SD): 2 - 24 hours

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h

Test conditions

Test temperature:
19.7-21.3°C
pH:
7.9-8.0
Dissolved oxygen:
8.3 - 8.5 mg/l
Nominal and measured concentrations:
Nominal test concentrations (mg/L): 12.5, 25, 50 and 100
Details on test conditions:
TEST SYSTEM
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 4
Reference substance (positive control):
yes
Remarks:
potassium dichromate

Results and discussion

Effect concentrationsopen allclose all
Duration:
48 h
Dose descriptor:
EC0
Effect conc.:
>= 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Remarks on result:
other: Nominal concentration verified analytically
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Remarks on result:
other: Nominal concentration verified analytically 95% CL
Duration:
48 h
Dose descriptor:
EC100
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Remarks on result:
other: Nominal concentration verified analytically

Any other information on results incl. tables

Cumulative immobility after x hours (%)

Nominal concentration (mg/l)

3 h

6 h

24 h

48 h

Control

Conc1

Conc2

Conc3

Conc4

Conc5

Conc6

Conc7

Conc8

Conc9

Applicant's summary and conclusion

Executive summary:

Administrative data: add

- Purpose flag if key study

- "used for MSDS" if key study

- data: Study period if possible, otherwise delete entry

Data source:

- add year

- add date

- add company study number or report number if stated

- Check performing laboratory

Test material: add

- CAS #

- Name of test material (as cited in study report)

- Analytical purity, physical state?

Vehicle: yes/no?

Test conditions: check

- Test temperature

- pH

- Dissolved oxygen

- nominal and measured concentrations

- Details on test conditions

- No of vessels per concentration

- No of vessels per control

Results and discussion: add

- Effect concentrations

Any other information on results incl. tables:

- fill in table, replace ConcX with the real test concentrations