Registration Dossier
Registration Dossier
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EC number: 278-014-3 | CAS number: 74878-48-1
Endpoint summary
Administrative data
Description of key information
Aquatic Chronic 3 (H412), according to the CLP Regulation (EC) No 1272/2008
Additional information
Adequate chronic toxicity data are not available for Fluorescent Brightener 363, therefore the aquatic toxicity assessment and classification are based mainly on the short-term toxicity available data.
Fluorescent Brightener 363 is very water soluble and it has a log Kow lower than 4, indicating a low potential for bioaccumulation. It is not rapidly degradable.
According to the CLP Regulation (EC) No 1272/2008, acute aquatic toxicity is normally determined using a fish 96-hour LC50, a crustacean species 48-hour EC50 and/or an algal species 72- or 96-hour EC50; these species cover a range of trophic levels and taxa and are considered as surrogate for all aquatic organisms.
Data are available for fish (Oncorhynchus mykiss, Leuciscus idus and Danio rerio), invertebrate (Daphnia magna) and algae (Pseudokirchneriella subcapitata). The outcomes of the tests performed on the three trophic levels suggest that Daphnia magna and Pseudokirchneriella subcapitata are the most sensitive species, thus the classification should be based on the related data.
No L(E)C50 value was recorded at concentration equal/lower than 1 mg/l, thus the classification criteria for acute (short-term) aquatic hazard (category 1) of the CLP Regulation (EC) No 1272/2008 are not met.
Studies about short-term toxicity to invertebrates and toxicity to aquatic algae fixed the short-term effect level in the range of 10 -100 mg/l, thus the substance meets the criteria to be classified as harmful to aquatic life with long lasting effects (category 3) of the CLP Regulation (EC) No 1272/2008.
In conclusion, the Fluorescent Brightener 363 is classified as Aquatic Chronic 3 (H412), according to the CLP Regulation (EC) No 1272/2008.
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