Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
in vivo mammalian somatic cell study: cytogenicity / erythrocyte micronucleus
Remarks:
Type of genotoxicity: chromosome aberration
Type of information:
experimental study planned
Study period:
Six months after ECHAs final decision.

Data source

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)
Qualifier:
according to guideline
Guideline:
EU Method B.12 (Mutagenicity - In Vivo Mammalian Erythrocyte Micronucleus Test)
Qualifier:
according to guideline
Guideline:
other: OECD Guideline 489: In Vivo Mammalian Alkaline Comet Assay
Type of assay:
micronucleus assay

Test material

Constituent 1
Chemical structure
Reference substance name:
[5-acetyl-2-(acetyloxy)phenyl]methyl acetate
EC Number:
921-042-4
Cas Number:
24085-06-1
Molecular formula:
C13-H14-O5
IUPAC Name:
[5-acetyl-2-(acetyloxy)phenyl]methyl acetate

Test animals

Species:
rat

Results and discussion

Applicant's summary and conclusion