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EC number: 206-117-5 | CAS number: 302-17-0
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
- Justification for type of information:
- Experimental test result performed using standard methods
- Qualifier:
- according to guideline
- Guideline:
- other: as mentioned below
- Principles of method if other than guideline:
- The solubility determination of test substance 2,2,2–trichloroethane-1,1-diol (CAS No. 302-17-0) in various organic solvents was done with acetone, acetonitrile, methanol, ethanol, toluene and Dimethylformamide (DMF).
- GLP compliance:
- no
- Specific details on test material used for the study:
- - Name of test material: 2,2,2-Trichloroethane-1,1-diol (Chloral hydrate)
- Molecular formula: C2-H3-Cl3-O2
- Molecular weight: 165.4026g/mol
- Smiles notation: C(C(O)O)(Cl)(Cl)Cl
- InChl: RNFNDJAIBTYOQL-UHFFFAOYSA-N
- Substance type: Organic
- Physical state: Solid - Key result
- Medium:
- acetone
- Solubility:
- > 1 000 g/L
- Temp.:
- 30 °C
- Key result
- Medium:
- acetonitrile
- Solubility:
- > 1 000 g/L
- Temp.:
- 30 °C
- Key result
- Medium:
- methanol
- Solubility:
- > 1 000 g/L
- Temp.:
- 30 °C
- Key result
- Medium:
- toluene
- Solubility:
- > 1 000 g/L
- Temp.:
- 30 °C
- Key result
- Medium:
- dimethylformamide
- Solubility:
- > 1 000 mg/L
- Temp.:
- 30 °C
- Key result
- Medium:
- ethanol
- Solubility:
- >= 200 - <= 1 000 g/L
- Temp.:
- 30 °C
- Test substance stable:
- not determined
- Conclusions:
- The solubility range of the substance 2,2,2–trichloroethane-1,1-diol(CAS No. 302-17-0)in acetone, acetonitrile, methanol, toluene and DMF was found to be greater than 1000 g/l. whereas the solubility range of the substance was found to be in the range of 200 – 1000 g/l in case of ethanol respectively.
- Executive summary:
The solubility determination of test substance2,2,2–trichloroethane-1,1-diol(CAS No. 302-17-0) in various organic solvents was done with acetone, acetonitrile, methanol, ethanol, toluene and Dimethylformamide (DMF). The solubility of the test substance in acetone, acetonitrile, methanol, toluene and DMF was found to be greater than 1000 g/l whereas the solubility value in ethanol was found to be in the range of 200 – 1000 g/l, respectively at 30 °C.
Reference
The solubility range of the substance 2,2,2–trichloroethane-1,1-diol(CAS No. 302-17-0)in acetone, acetonitrile, methanol, toluene and DMF was found to be greater than 1000 g/l. whereas the solubility range of the substance was found to be in the range of 200 – 1000 g/l in case of ethanol respectively.
Description of key information
The solubility determination of test substance2,2,2–trichloroethane-1,1-diol(CAS No. 302-17-0) in various organic solvents was done with acetone, acetonitrile, methanol, ethanol, toluene and Dimethylformamide (DMF). The solubility of the test substance in acetone, acetonitrile, methanol, toluene and DMF was found to be greater than 1000 g/l whereas the solubility value in ethanol was found to be in the range of 200 – 1000 g/l, respectively at 30 °C.
Key value for chemical safety assessment
- Solubility in organic solvents at 20°C:
- 1 000 g/L
Additional information
The solubility determination of test substance2,2,2–trichloroethane-1,1-diol(CAS No. 302-17-0) in various organic solvents was done with acetone, acetonitrile, methanol, ethanol, toluene and Dimethylformamide (DMF). The solubility of the test substance in acetone, acetonitrile, methanol, toluene and DMF was found to be greater than 1000 g/l whereas the solubility value in ethanol was found to be in the range of 200 – 1000 g/l, respectively at 30 °C.
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