Registration Dossier
Registration Dossier
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EC number: 255-138-6 | CAS number: 40910-49-4
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
The old 1980 GPMT indicated very slight erythema at 10% challenge in 3 animals but not at 5% challenge. This study was conducted in 1980 has deficiencies and is not suitable as a standalone test to indicate classification. Therefore 2 in vitro assays (DPRA and KeratinoSens) were conducted. These 2 in vitro assays indicate no reactions sufficient for classification.
Migrated from Short description of key information:
Old 1980 GPMT. Two new in vitro assays conducted indicate no reactions.
Justification for selection of skin sensitisation endpoint:
GPMT and in vitro DPRA and KeratinoSens
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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