1,4-divinylbenzene

Toxicity to aquatic algae and cyanobacteria

Link to relevant study record(s)

Reference

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

calculation (if not (Q)SAR)

Remarks:

Migrated phrase: estimated by calculation

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Qualifier:

according to guideline

Guideline:

other: Modeling database

Principles of method if other than guideline:

ECOSAR v1.1

GLP compliance:

no

Specific details on test material used for the study:

- Name of test material (IUPAC Name): 1,4-Bis(ethenyl)benzene- Common name: p-Divinylbenzene- Molecular formula: C10H10- Molecular weight: 130.189 g/mol- Smiles notation: C(c1ccc(cc1)C=C)=C- InChI: 1S/C10H10/c1-3-9-5-7-10(4-2)8-6-9/h3-8H,1-2H2 - Substance type: Organic- Physical state: Solid- Water solubility: 8.2 mg/l

Test organisms (species):

other: green algae

Test type:

not specified

Water media type:

not specified

Key result

Duration:

96 h

Dose descriptor:

EC50

Effect conc.:

2.58 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

growth rate

Remarks on result:

other: No other details available

Conclusions:

The short-term toxicity of the 1,4-Bis(ethenyl)benzene; p-Divinylbenzene (CAS no.105-06-6 ) to Green algae is predicted using EPI Suite ECOSAR version 1.10. On the basis of effects observed in a static freshwater system during a 96 hr exposure, the effect concentration (EC50) for the substance is estimated to be 2.580 mg/L. Based on this value, it can be concluded that the test chemical can be considered as toxic to Green Alage at environmentally relevant concentrations and can be considered as classified in aquatic chronic category 2 as per the CLP classification criteria.

Executive summary:

The short-term toxicity of the 1,4-Bis(ethenyl)benzene; p-Divinylbenzene (CAS no.105-06-6 ) to Green algae is predicted using EPI Suite ECOSAR version 1.10. On the basis of effects observed in a static freshwater system during a 96 hr exposure, the effect concentration (EC50) for the substance is estimated to be 2.580 mg/L. Based on this value, it can be concluded that the test chemical can be considered as toxic to Green Alage at environmentally relevant concentrations and can be considered as classified in aquatic chronic category 2 as per the CLP classification criteria.

Description of key information

The short-term toxicity of the 1,4-Bis(ethenyl)benzene; p-Divinylbenzene (CAS no.105-06-6 ) to Green algae is predicted using EPI Suite ECOSAR version 1.10. On the basis of effects observed in a static freshwater system during a 96 hr exposure, the effect concentration (EC50) for the substance is estimated to be 2.580 mg/L. Based on this value, it can be concluded that the test chemical can be considered as toxic to Green Alage at environmentally relevant concentrations and can be considered as classified in aquatic chronic category 2 as per the CLP classification criteria.

Key value for chemical safety assessment

EC50 for freshwater algae:

2.58 mg/L

Additional information

The short-term toxicity of the 1,4-Bis(ethenyl)benzene; p-Divinylbenzene (CAS no.105-06-6 ) to Green algae is predicted using EPI Suite ECOSAR version 1.10. On the basis of effects observed in a static freshwater system during a 96 hr exposure, the effect concentration (EC50) for the substance is estimated to be 2.580 mg/L. Based on this value, it can be concluded that the test chemical can be considered as toxic to Green Alage at environmentally relevant concentrations and can be considered as classified in aquatic chronic category 2 as per the CLP classification criteria.