Registration Dossier

Administrative data

Endpoint:
acute toxicity: dermal
Adequacy of study:
other information

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: 92/69/EWG, B.3
GLP compliance:
yes
Limit test:
yes

Test animals

Species:
other: rat, Wistar Crl:(WI) BR

Administration / exposure

Type of coverage:
semiocclusive
Vehicle:
other: No vehicle used. The test article was moistened with distilled water.
Duration of exposure:
24 h

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Mortality:
Male: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Clinical signs:
Signs of toxicity related to dose levels:
No treatment related mortality, clinical signs were noted.
Most animals showed a reduced weight gain in the first week
after treatment.
Gross pathology:
Effects on organs:
No treatment related macroscopic findings were noted.
Other findings:
Signs of toxicity (local):
No treatment related skin reactions were noted.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU